William Shatner plays two roles: cowboy Johnny Moon and his ruthless Indian twin brother, Notah. Notah likes peyote and gets the crazy idea that he's the Comanche messiah sent to lead the Comanche nation against the white man but more specifically the dusty desert town of Rio Hondo. Moon, estranged from his brother, decides to stop Notah either by words or by bullets.
Joseph Cotten
Sheriff Logan
William Shatner
Johnny Moon / Notah
Rosanna Yanni
Kelly
Perla Cristal
White Fawn
Mariano Vidal Molina
General Garcia
Luis Prendes
Grimes
Barta Barri
Major Bolker
Víctor Israel
Carter
