Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.
Robert De Niro
Leonard Lowe
Robin Williams
Malcolm Sayer
John Heard
Dr. Kaufman
Julie Kavner
Eleanor Costello
Penelope Ann Miller
Paula
Ruth Nelson
Mrs. Lowe
Max von Sydow
Peter Ingham
Anne Meara
Miriam
